Seminario 17-1-2020. Symmetry Breaking in Chiral Crystallization: Pharmaceuticals and the Origin of Life.

Ponente: Cristóbal Viedma. Universidad Complutense de Madrid (UCM)

Día: 17 de enero de 2020
Hora: 12:00

Lugar: Auditorio del Centro de Astrobiología
Instituto Nacional de Técnica Aeroespacial (INTA)
Ctra. de Ajalvir, Km.4
28850 Torrejón de Ardoz (Madrid)


** Entrada: necesario registro en el correo seminarios@cab.inta-csic.es indicando nombre y DNI y datos de tu vehículo (marca, modelo y matrícula). ***



Título: Symmetry Breaking in Chiral Crystallization: Pharmaceuticals and the Origin of Life.

Resumen: The homochirality of biological molecules – right-handed sugars and left-handed amino acids – is a signature of life. The single handedness in living systems implies that the two enantiomers of a molecule interact differently with chiral receptors. Synthesis of enantiopure compounds is a major challenge for the pharmaceutical industry as generally only one of the two enantiomers exerts the desired medical effect. Current ideas on the origin of life do not explain the origin of homochirality, yet the widely accepted ‘RNA world’ model cannot work without it. The origin of homochirality in nature has puzzled and mesmerized scientists from Pasteur’s times. This talk will summarize the experiments, hypothesis, results, and of course a touch of serendipity, which led us to exploiting racemization as the driving force for homochirality. Under certain conditions, one enantiomer nurtures the other in an autocatalytic fashion that evolves into single handedness.


Departamentos y unidades de apoyo

La respuesta a las cuestiones sobre la vida y su origen ha de venir del esfuerzo combinado de muchas disciplinas

Grupos de investigación

La ciencia desarrollada en el CAB se canaliza a través de grupos de investigación interdepartamentales

Cultura Científica

La UCC del CAB busca hacer accesible el conocimiento científico al conjunto de los ciudadanos

Copyright 2012 - Todos los derechos reservados | Centro de Astrobiología - CSIC - INTA | Política y condiciones de uso | Aviso legal